Jednostki i pracownicy - książka adresowa

dr Magdalena Mizerska-Kowalska

dr Magdalena Mizerska-Kowalska
Stanowisko
adiunkt
Jednostki
KATEDRA WIRUSOLOGII I IMMUNOLOGII
Telefon
815375951
Adres e-mail
Wyświetl
Strona www
https://orcid.org/0000-0003-2364-6181
https://www.researchgate.net/profile/Magdalena-Mizerska-Kowalska
Konsultacje

Konsultacje semestr letni 2021/2022


środa 13.30 - 14.30 (stacjonarnie)


czwartek 11.00 - 12.00 (stacjonarnie)


pokój 310 (Wydział Biologii i Biotechnologii)


 


W dniu 31.03.2022 z powodu urlopu konsultacje są odwołane.


W dniu 06 i 07.04.2022 z powodu wyjazdu służbowego konsultacje są odwołane.

Adres

ul. Akademicka 19
Lublin

O sobie

Działalność dydaktyczna/Teaching:

Ćwiczenia: Immunologia; Wirusologia/Wirusologia ogólna i lekarska;

Wykład: Produkcja szczepionek i przeciwciał.

Laboratories (in English): Human Immunology with Elements of Virology; Immunology; Virology; General and medical virology (Medical Biology and Erasmus)

Lecture (in English): Human Immunology with Elements of Virology

 

Wykształcenie:

Maria Curie-Skłodowska University, Lublin, specialization: biological sciences, microbiology
MSc (2005)
PhD (2010)


Działalność naukowa

The general scopes of scientific interests:

the anti-tumor and anti-viral; osteogenesis-promoting; immunostimulating/immunomodulating activities of substances/compounds/extracts of natural, semi-synthetic, synthetic origin and molecular mechanisms of their activities - in vitrostudies

The main scientific interests:

the engagement of neutral endopeptidase (NEP, neprilysin, CD10) in biology of tumors, e.g. colon cancer and osteosarcoma and natural, semi-synthetic, synthetic compounds with anti-tumor potential and down-regulating or inhibiting activity of NEP

Grants of National Science Center of Poland:

The role of neutral endopeptidase (NEP) and its inhibitor, sialorphin, in colon cancer cells biology, finished (supervisor Prof. dr hab. M. Kandefer-Szerszeń; editor, main executor dr M. Mizerska-Kowalska)

The evaluation of alfa-ketoglutarate (AKG) influence on level and activity of neutral endopeptidase (NEP) in tumor cells, finhished (editor, supervisor and main executor dr M. Mizerska-Kowalska)

Patents:

Lacasse enzyme isolated from Cerrena unicolor to be applied in the cervical carcinoma treatment. Patent no 40657313
 
Protein-sugar fraction isolated from the coelomic fluid of Dendrobaena veneta earthworm for application in non-specific immunotherapy. Patent no 238444
 

Patent applications:

[1-(N-p-bromophenylamino)]-1-(p-nitrophenyl)methylphosphonous acid-borane diisopropyl ester to be applied in the osteosarcoma treatment. Application no P.438017
 
[1-(N-p-bromophenylamino)]-1-(p-nitrophenyl)methylphosphonous acid-borane diisopropyl ester to be applied as inhibitor of neutral endopeptidase. Application no P.440633
 
Skills: colorimetric and fluorometric methods used for cell proliferation and viability evaluation; flow cytometry, RT-PCR, Western Blott, immunofluorescence and ELISA used for evaluation of expression level of extra- and intracellular proteins; wound closure and transwell-based assays to determine the metastatic activities of tumor cells, basic in silico analysis (ADME) on biologically active small molecular compounds; establishment of chicken fibroblast cell culture; viruses cultivation in cell cultures and chicken embryos; biological methods of evaluation of antiviral activity of any substances/compounds; biological evaluation of medical devices tests for in vitro cytotoxicity